BDBM98630 US8497376, 11

SMILES CC1(C)O[C@H]2[C@@H](O1)[C@]1(C)C[C@](O)(C[C@@]2(C)O1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1

InChI Key InChIKey=OPOZRFIOYLHLDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98630   

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM98630(US8497376, 11)
Affinity DataIC50: 1.80nMpH: 7.5Assay Description:An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2013
Entry Details
Go to US Patent