BDBM98587 (2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimidoylphenyl)methylamino]-2-oxo-ethyl]-2-(benzylsulfonylamino)-3-hydroxy-propanamide::US8476306, 6.13

SMILES NC(=N)c1ccc(CNC(=O)[C@H](COCc2ccccc2)NC(=O)[C@@H](CO)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key InChIKey=RLZYVXBJYQEXBP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98587   

TargetSerine protease 1(Rat)
The Medicines

US Patent
LigandPNGBDBM98587((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)
Affinity DataKi:  6.80nM ΔG°:  -11.1kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
Go to US Patent

TargetUrokinase plasminogen activator surface receptor(Rat)
The Medicines

US Patent
LigandPNGBDBM98587((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)
Affinity DataKi:  28nM ΔG°:  -10.3kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
Go to US Patent

TargetPlasminogen(Rat)
The Medicines

US Patent
LigandPNGBDBM98587((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)
Affinity DataKi:  270nM ΔG°:  -8.92kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
Go to US Patent

TargetProthrombin(Rat)
The Medicines

US Patent
LigandPNGBDBM98587((2R)-N-[(1S)-1-(benzyloxymethyl)-2-[(4-carbamimido...)
Affinity DataKi:  480nM ΔG°:  -8.59kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2013
Entry Details
Go to US Patent