BDBM98552 US8492387, 66

SMILES COc1ccc(cc1)C(Cc1ccc(cc1)-c1ccc(=O)[nH]c1)c1cn(C)c(N)n1

InChI Key InChIKey=CGSKUTVDJXNMIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98552   

TargetBeta-secretase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM98552(US8492387, 66)
Affinity DataIC50: 1.70E+4nMpH: 6.5Assay Description:End point electrochemiluminescence (ECL) assay: a homogeneous ECL assay is performed using a biotinylated BACE substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
Go to US Patent