BDBM98541 US8492392, 1-13

SMILES COc1cc(NC(=O)N2CCc3nc(nc(OC4CCOC4)c3C2)-c2ccc(Cl)nc2)ccn1

InChI Key InChIKey=OZPYHEOGSYUAKC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98541   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM98541(US8492392, 1-13)
Affinity DataKi:  0.840nM ΔG°:  -12.4kcal/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
Go to US Patent