BDBM98534 US8492392, N-5

SMILES CC(C)Oc1nc(nc2CCN(Cc12)C(=O)Nc1ccc(C)nc1)N1CCCC1

InChI Key InChIKey=LMCFZWMTKXPNBX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98534   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM98534(US8492392, N-5)
Affinity DataKi:  31.4nM ΔG°:  -10.2kcal/moleT: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2013
Entry Details
Go to US Patent