BDBM98453 US8481733, 265

SMILES Nc1nccn2c(nc(-c3ccc(cc3)-c3csc4ccccc34)c12)C1CCC1

InChI Key InChIKey=LYGBXVIWUZAEMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 98453   

TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98453(US8481733, 265)
Affinity DataIC50: 4.09E+3nMAssay Description:Compounds of the invention were tested for ACK1 inhibition activity. 1 uL compounds prepared at 15× in 4 mM DMSO were combined with 9 uL ATP so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
Go to US Patent

TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98453(US8481733, 265)
Affinity DataIC50: 4.09E+3nMAssay Description:Inhibition of ACK1 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed