BDBM98450 US8481733, 262

SMILES C[C@@]1(O)C[C@@H](C1)c1nc(-c2ccc(C(=O)c3ccccc3)c(N)c2)c2c(N)nccn12

InChI Key InChIKey=URKDEQMCPCDLNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98450   

TargetActivated CDC42 kinase 1(Human)
Osi Pharmaceuticals

US Patent
LigandPNGBDBM98450(US8481733, 262)
Affinity DataIC50: 50nMAssay Description:Compounds of the invention were tested for ACK1 inhibition activity. 1 uL compounds prepared at 15× in 4 mM DMSO were combined with 9 uL ATP so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2013
Entry Details
Go to US Patent