BDBM98020 US8486966, 17

SMILES C[C@H](Nc1ccc2ncn(-c3cc(C)[nH]n3)c2n1)c1ccc(F)cn1

InChI Key InChIKey=VSWZVURJMXGYKU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 98020   

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca

US Patent
LigandPNGBDBM98020(US8486966, 17)
Affinity DataIC50: 3nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
Go to US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM98020(US8486966, 17)
Affinity DataIC50: 14nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
Go to US Patent