BDBM98018 US8486966, 14

SMILES CC(C)Oc1cc(n[nH]1)-n1cnc2cc(Cl)c(N[C@@H](C)c3ccc(F)cn3)nc12

InChI Key InChIKey=DNRJRDDATFHQGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98018   

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM98018(US8486966, 14)
Affinity DataIC50: 4nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
Go to US Patent