BDBM97715 US8476271, 96::US8846929, 356::US9145408, 356
SMILES OC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CC[C@H](C2)N3C2CCCCCCCCCCC2)c1=O
InChI Key InChIKey=DNQQJKRDKSYDKP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 97715
Affinity DataEC50: 686nMpH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like (ORL-1) (Receptor Biology) were prepared by lysing cells in ice-co...More data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane solution was prepared by sequentially adding final...More data for this Ligand-Target Pair
Affinity DataKi: 43.1nM ΔG°: -10.0kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 μg membrane protein in a ...More data for this Ligand-Target Pair
Affinity DataKi: 43.1nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
Affinity DataKi: 43.1nM ΔG°: -9.33kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Receptor Biology) were prepared by lysing cells ...More data for this Ligand-Target Pair
Affinity DataKi: 76nM ΔG°: -9.71kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane prot...More data for this Ligand-Target Pair
Affinity DataKi: 76nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4-0.8nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 ug membrane protein (recombinant kappa opioid receptor...More data for this Ligand-Target Pair
Affinity DataKi: 76nM ΔG°: -9.02kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned in house) were prepared by lysing cells in ice co...More data for this Ligand-Target Pair
Affinity DataKi: 1.44E+3nM ΔG°: -7.97kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose displacement assays used 0.4-0.8 nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 μg membrane protein (recombinant kappa opioid rece...More data for this Ligand-Target Pair
Affinity DataKi: 1.44E+3nMpH: 7.4Assay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.2nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20mg membrane protein/w...More data for this Ligand-Target Pair
Affinity DataKi: 1.44E+3nM ΔG°: -7.97kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane protei...More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+4nM ΔG°: -6.46kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20 mg membrane prot...More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+4nMpH: 7.4Assay Description:Radioligand dose-displacement assays used 0.2nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20ug membrane protein (recombinant delta opioid recepto...More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+4nM ΔG°: -6.46kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 ug membrane protein (recombinant delta opioid recep...More data for this Ligand-Target Pair