BDBM97611 CHEMBL1630712::US8470841, 36

SMILES CC(CCc1ccc(Oc2ccc(OCc3ccccc3)nc2)cc1)NC(C)=O

InChI Key InChIKey=AZMYOENOJLRPHJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 97611   

TargetAcetyl-CoA carboxylase 2 [151-2458](Human)
Sanofi

US Patent
LigandPNGBDBM97611(CHEMBL1630712 | US8470841, 36)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:The reaction mixture contained 50 mM tris acetate (Merck, #1.08382.1000), pH 7.5, 250 μM acetyl coenzyme A (Sigma, #A2181),16 mM NaHCO3 (Merck, #1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 1(Rat)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM97611(CHEMBL1630712 | US8470841, 36)
Affinity DataIC50: 700nMAssay Description:Inhibition of N-terminal His-tagged rat recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM97611(CHEMBL1630712 | US8470841, 36)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC1 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM97611(CHEMBL1630712 | US8470841, 36)
Affinity DataIC50: 80nMAssay Description:Inhibition of N-terminal His-tagged human recombinant ACC2 expressed in high five insect cells by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed