BDBM9757 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid deriv. 28::tert-butyl N-[(1S)-1-cyclohexyl-2-[(3S)-3-({1-[({[(S)-(dimethylcarbamoyl)(phenyl)methyl]carbamoyl}methyl)carbamoyl]-4-methyl-1-oxopentan-2-yl}carbamoyl)-2-azabicyclo[2.2.1]heptan-2-yl]-2-oxoethyl]carbamate

SMILES CC(C)CC(NC(=O)[C@@H]1C2CCC(C2)N1C(=O)[C@@H](NC(=O)OC(C)(C)C)C1CCCCC1)C(=O)C(=O)NCC(=O)N[C@H](C(=O)N(C)C)c1ccccc1

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9757   

TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM9757(tert-butyl N-[(1S)-1-cyclohexyl-2-[(3S)-3-({1-[({[...)
Affinity DataKi:  53nM ΔG°:  -10.1kcal/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2006
Entry Details Article
PubMed