BDBM97563 US8470825, 4i

SMILES OC1CCN(Cc2ccc3oc4cccc5c4c(n[nH]c5=O)c3c2)CC1

InChI Key InChIKey=HAVFFEMDLROBGI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 97563   

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandPNGBDBM97563(US8470825, 4i)
Affinity DataIC50: 40nMpH: 8.0 T: 2°CAssay Description:The PARP enzyme assay is set up on ice in a volume of 100 microliters consisting of 100 mM Tris-HCl (pH 8.0), 1 mM MgCl2, 28 mM KCl, 28 mM NaCl, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2013
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandPNGBDBM97563(US8470825, 4i)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PARP1 (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Eisai

US Patent
LigandPNGBDBM97563(US8470825, 4i)
Affinity DataKi:  50nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed