BDBM9611 (R)-N-(1S,2R)-[3-[2-[[(1,1-Dimethylethyl)-amino]carbonyl]phenyl]-2-hydroxy-1-(phenylmethyl)-propyl]-2-[(n-propylcarbonyl)amino]-4-oxo-4-(benzyloxy)-butanamide::Carboxamide analog 6::benzyl (3R)-3-butanamido-3-{[(2S,3R)-4-[2-(tert-butylcarbamoyl)phenyl]-3-hydroxy-1-phenylbutan-2-yl]carbamoyl}propanoate

SMILES CCCC(=O)N[C@H](CC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)Cc1ccccc1C(=O)NC(C)(C)C

InChI Key InChIKey=GKEZUQAKQIACNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9611   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM9611((R)-N-(1S,2R)-[3-[2-[[(1,1-Dimethylethyl)-amino]ca...)
Affinity DataIC50: 323nMpH: 5.5 T: 2°CAssay Description:The assay involves the use of a HIV-1 protease peptide substrate which has been modified to contain a biotin moiety on one side and a fluorescent rep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2006
Entry Details Article
PubMed