BDBM9575 4-({[(2R,3S,4S,5R)-1,5,6-tris[(4-cyanophenyl)methoxy]-3,4-dihydroxyhexan-2-yl]oxy}methyl)benzonitrile::tetra-O-benzyl-d-mannitol deriv. 1e

SMILES O[C@H]([C@@H](COCc1ccc(cc1)C#N)OCc1ccc(cc1)C#N)[C@H](O)[C@@H](COCc1ccc(cc1)C#N)OCc1ccc(cc1)C#N

InChI Key InChIKey=GMRLNLALZAJUCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9575   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9575(4-({[(2R,3S,4S,5R)-1,5,6-tris[(4-cyanophenyl)metho...)
Affinity DataIC50: 3.10E+3nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2006
Entry Details Article
PubMed