BDBM9464 1-(9H-Fluoren-9-yl)-1H-imidazole::CHEMBL225447::Fluorenyl deriv. 13

SMILES c1cn(cn1)C1c2ccccc2-c2ccccc12

InChI Key InChIKey=TULIZIRHYBBLAI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9464   

TargetAromatase(Human)
University of Bari

LigandPNGBDBM9464(1-(9H-Fluoren-9-yl)-1H-imidazole | CHEMBL225447 | ...)
Affinity DataIC50: 2.85E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta, 2beta-3H] testosterone or [1beta-3H] androstenedione during aroma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2006
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bari

LigandPNGBDBM9464(1-(9H-Fluoren-9-yl)-1H-imidazole | CHEMBL225447 | ...)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bari

LigandPNGBDBM9464(1-(9H-Fluoren-9-yl)-1H-imidazole | CHEMBL225447 | ...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed