BDBM93427 PHD Inhibitor, 12{2,6,2}

SMILES CC(C)C[C@H](NC(C)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)NCc1ccc2n(C)c(=O)c(C(=O)NCC(O)=O)c(O)c2c1

InChI Key InChIKey=DXQATEPEYBQMGM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 93427   

TargetEgl nine homolog 1(Human)
Amgen

LigandPNGBDBM93427(PHD Inhibitor, 12{2,6,2})
Affinity DataIC50: 67.5nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Amgen

LigandPNGBDBM93427(PHD Inhibitor, 12{2,6,2})
Affinity DataIC50: 11nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Amgen

LigandPNGBDBM93427(PHD Inhibitor, 12{2,6,2})
Affinity DataIC50: 16.2nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed