BDBM93419 PHD Inhibitor, 12{2,4,1}

SMILES Cn1c2ccc(CNC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)c3ccccc3)cc2c(O)c(C(=O)NCC(O)=O)c1=O

InChI Key InChIKey=JMKSCVGKOMWIJH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 93419   

TargetEgl nine homolog 1(Human)
Amgen

LigandPNGBDBM93419(PHD Inhibitor, 12{2,4,1})
Affinity DataIC50: 622nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Amgen

LigandPNGBDBM93419(PHD Inhibitor, 12{2,4,1})
Affinity DataIC50: 22nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Amgen

LigandPNGBDBM93419(PHD Inhibitor, 12{2,4,1})
Affinity DataIC50: 20nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Amgen

LigandPNGBDBM93419(PHD Inhibitor, 12{2,4,1})
Affinity DataIC50: 38.3nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Amgen

LigandPNGBDBM93419(PHD Inhibitor, 12{2,4,1})
Affinity DataIC50: 8.5nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Amgen

LigandPNGBDBM93419(PHD Inhibitor, 12{2,4,1})
Affinity DataIC50: 5.30nMAssay Description:PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2013
Entry Details Article
PubMed