BDBM93168 Cathepsin Inhibitor, Column 1 Row 1

SMILES CC(C)C[C@H](NC(C)=O)C(=O)NC(C)C(=O)CNC(=O)Cc1cccc(c1)-c1ccccn1

InChI Key InChIKey=RECJGPBCNCVZPI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 93168   

TargetCathepsin K(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM93168(Cathepsin Inhibitor, Column 1 Row 1)
Affinity DataKi:  200nMpH: 5.5Assay Description:Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetCathepsin L(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM93168(Cathepsin Inhibitor, Column 1 Row 1)
Affinity DataKi: >1.00E+3nMpH: 5.5Assay Description:Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM93168(Cathepsin Inhibitor, Column 1 Row 1)
Affinity DataKi: >1.00E+3nMpH: 5.5Assay Description:Inhibitors were assayed against human liver Cathepsin L and B. Inhibitors were also evaluated for inhibition against purified recombinant Cathepsin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed