BDBM93125 Trisubsituted thiazole, 15

SMILES OCCCc1sc(CCC(=O)CSCCCc2ccccc2)nc1CCc1ccccc1

InChI Key InChIKey=BJRKTVHPLBHMBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 93125   

TargetCysteine proteinase falcipain 2a(malaria parasite P. falciparum)
University, Mississippi

LigandPNGBDBM93125(Trisubsituted thiazole, 15)
Affinity DataIC50: 1.25E+4nMAssay Description:In vitro antimalarial assay, antimalarial activity of the compounds was determined in vitro on chloroquine sensitive and resistant strains of plasmod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2013
Entry Details Article

TargetCysteine proteinase falcipain 3(Plasmodium falciparum (isolate 3D7))
University, Mississippi

LigandPNGBDBM93125(Trisubsituted thiazole, 15)
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro antimalarial assay, antimalarial activity of the compounds was determined in vitro on chloroquine sensitive and resistant strains of plasmod...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2013
Entry Details Article