BDBM93094 2-Guanidino-4-methylguinazoline

SMILES Cc1nc(NC(N)=N)nc2ccccc12

InChI Key InChIKey=ONQKSKDLYYDFLL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 93094   

TargetMyeloperoxidase(Human)
Free University of Brussels

Curated by ChEMBL
LigandPNGBDBM93094(2-Guanidino-4-methylguinazoline)
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2019
Entry Details Article
PubMed
TargetComplement C1s subcomponent(Human)
Michigan State University

LigandPNGBDBM93094(2-Guanidino-4-methylguinazoline)
Affinity DataKi:  7.65E+4nM ΔG°:  -5.62kcal/molepH: 8.05 T: 2°CAssay Description:All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2013
Entry Details Article
PubMed