BDBM92870 4-Aminoquinazoline derivative, 6d

SMILES Cc1ccc(Nc2ncnc3cc(OCCCN4CCCC4)ccc23)cc1Nc1ncc(cn1)-c1cccnc1

InChI Key InChIKey=IESKIIZEQNQSBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92870   

TargetAurora kinase A(Human)
Southeast University

LigandPNGBDBM92870(4-Aminoquinazoline derivative, 6d)
Affinity DataIC50: 77nMAssay Description:The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Southeast University

LigandPNGBDBM92870(4-Aminoquinazoline derivative, 6d)
Affinity DataIC50: 145nMAssay Description:The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed