BDBM92869 4-Aminoquinazoline derivative, 6c

SMILES CCN(CC)CCCOc1ccc2c(Nc3ccc(C)c(Nc4ncc(cn4)-c4cccnc4)c3)ncnc2c1

InChI Key InChIKey=WQIDEXUPWOIQDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92869   

TargetAurora kinase A(Human)
Southeast University

LigandPNGBDBM92869(4-Aminoquinazoline derivative, 6c)
Affinity DataIC50: 98nMAssay Description:The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Southeast University

LigandPNGBDBM92869(4-Aminoquinazoline derivative, 6c)
Affinity DataIC50: 202nMAssay Description:The kinase assay of Aurora A and B was measured using HTRF-kinEASE-STK discovery kit purchased from Cisbio.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2013
Entry Details Article
PubMed