BDBM92861 PncA Inhibitor, 6

SMILES N#Cc1cnccn1

InChI Key InChIKey=PMSVVUSIPKHUMT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92861   

TargetHistone deacetylase 8(Human)
Hun-Ren Research Centre for Natural Sciences

Curated by ChEMBL
LigandPNGBDBM92861(PncA Inhibitor, 6)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(TFA)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPyrazinamidase/nicotinamidase PncA(Mycobacterium tuberculosis)
Albert Einstein College of Medicine

LigandPNGBDBM92861(PncA Inhibitor, 6)
Affinity DataKi:  6.10E+4nMAssay Description:Enzyme activity measurement by a coupled assay. initial velocities for the reaction of MtPncA were determined by monitoring the loss of absorbance a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed