BDBM92604 DHOD Inhibitor, 3::US8703811, 1

SMILES CCCNC(=O)c1ccc(s1)-n1c(C)cc2ccccc12

InChI Key InChIKey=OQYMMMMIAASALW-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 92604   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 420nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei (strain Anka))
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 60nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 420nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 3.00E+4nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 42nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei (strain Anka))
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 60nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium vivax)
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 420nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (fumarate)(Baker's yeast)
Genzyme

US Patent
LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 3.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 64nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(malaria parasite P. falciparum)
Harvard Medical School

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 70nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent

LigandPNGBDBM92604(US8703811, 1 | DHOD Inhibitor, 3)
Affinity DataIC50: 3.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
Go to US Patent