BDBM92528 Aminopyrazole inhibitor, 4643

SMILES Cc1cncc(NC(=O)c2cc(cc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)N2CCOCC2)c1

InChI Key InChIKey=SCYPRAPAYLZPID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 92528   

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

LigandPNGBDBM92528(Aminopyrazole inhibitor, 4643)
Affinity DataIC50: 1.50E+3nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandPNGBDBM92528(Aminopyrazole inhibitor, 4643)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
The Scripps Research Institute

LigandPNGBDBM92528(Aminopyrazole inhibitor, 4643)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed