BDBM92523 Aminopyrazole inhibitor, 3528

SMILES COc1cc(NC(=O)c2cccc(c2)-n2cc(NC(=O)Nc3ccccc3Cl)cn2)cc(OC)c1OC

InChI Key InChIKey=PANZFUIIZSOBRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 92523   

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

LigandPNGBDBM92523(Aminopyrazole inhibitor, 3528)
Affinity DataIC50: 23nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

LigandPNGBDBM92523(Aminopyrazole inhibitor, 3528)
Affinity DataIC50: 560nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 13(Human)
The Scripps Research Institute

LigandPNGBDBM92523(Aminopyrazole inhibitor, 3528)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:Homogeneous time-resolved fluorescence assay is an enzyme inhibition studies that were performed in 384-well polystyrene homogeneous time-resolved fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed