BDBM92474 Sulfonamide, 5

SMILES COc1cc(OC)c(cc1NC(=O)CCC(O)=O)S(=O)(=O)N1c2ccccc2Oc2ccccc12

InChI Key InChIKey=HXWWKCKINGLXEB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 92474   

TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: 7nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetBifunctional protein GlmU(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: 23nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetBifunctional protein GlmU(Streptococcus pneumoniae)
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: 1.50E+4nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetBifunctional protein GlmU(Staphylococcus aureus (Firmicutes))
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: 2.00E+5nMpH: 7.35Assay Description:Inhibition assay using GlmU bifuncation enzyme with various bacterial strains.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli GlmU acetyltransferase activity assessed as coenzyme A production using acetyl CoA substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed
TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Astrazeneca

LigandPNGBDBM92474(Sulfonamide, 5)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli GlmU acetyltransferase activity assessed as coenzyme A production using acetyl CoA substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2016
Entry Details Article
PubMed