BDBM92358 HGXPRT Inhibitor, 3

SMILES OC[C@H](CCP([O-])([O-])=O)[NH2+]c1c[nH]c2c1nc[nH]c2=O

InChI Key InChIKey=QYVPBNMGNCACHL-UHFFFAOYSA-M

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 92358   

TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
Albert Einstein College of Medicine

LigandPNGBDBM92358(HGXPRT Inhibitor, 3)
Affinity DataKi:  0.650nM ΔG°:  -13.0kcal/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2012
Entry Details Article
PubMed
TargetHypoxanthine-guanine phosphoribosyltransferase(Human)
Albert Einstein College of Medicine

LigandPNGBDBM92358(HGXPRT Inhibitor, 3)
Affinity DataKi:  385nM ΔG°:  -9.10kcal/molepH: 7.6 T: 2°CAssay Description:PfHGXPRT activity was measured using spectrophotometric assay observing the conversion of xanthine and 5-phospho-alpha-D-ribose-1-pyrophosphate to xa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2012
Entry Details Article
PubMed