BDBM9202 (2R,4S)-2-benzyl-5-[(5S)-5-benzyl-2-oxo-3-[(3,4,5-trimethoxyphenyl)methyl]imidazolidin-1-yl]-4-hydroxy-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]pentanamide::2-imidazolidinone scaffold 18

SMILES COc1cc(CN2C[C@H](Cc3ccccc3)N(C[C@@H](O)C[C@@H](Cc3ccccc3)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34)C2=O)cc(OC)c1OC

InChI Key InChIKey=JLGIMFVIPMQTEL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 9202   

TargetDimer of Gag-Pol polyprotein [501-599,Q508K,L534I,L564I,C568A,C596A](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM9202((2R,4S)-2-benzyl-5-[(5S)-5-benzyl-2-oxo-3-[(3,4,5-...)
Affinity DataKi:  100nM ΔG°:  -9.54kcal/molepH: 6.4 T: 2°CAssay Description:The Ki values were determined using fluorogenic substrate, 2-(aminobenzoyl)-Thr-Ile-Nle-Phe(p-NO2)-Gln-ArgNH2. A standard curve relating changes in f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2006
Entry Details Article
PubMed