BDBM91461 5-[4-(dimethylamino)benzylidene]-3-(2-furfuryl)-2-thioxo-thiazolidin-4-one::5-[[4-(dimethylamino)phenyl]methylidene]-3-(2-furanylmethyl)-2-sulfanylidene-4-thiazolidinone::5-[[4-(dimethylamino)phenyl]methylidene]-3-(furan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one::MLS003115998::SMR001831556::US20230364057, Compound 228::cid_330810

SMILES CN(C)c1ccc(C=C2SC(=S)N(Cc3ccco3)C2=O)cc1

InChI Key InChIKey=VXQGBGAKYBGKCS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 91461   

TargetCorticotropin-releasing factor-binding protein(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM91461(5-[[4-(dimethylamino)phenyl]methylidene]-3-(2-fura...)
Affinity DataEC50:  3.20E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM91461(5-[[4-(dimethylamino)phenyl]methylidene]-3-(2-fura...)
Affinity DataIC50: 1.25E+5nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent

TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM91461(5-[[4-(dimethylamino)phenyl]methylidene]-3-(2-fura...)
Affinity DataIC50: 1.25E+5nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
US Patent