BDBM9046 Homodimeric Tacrine Analog 2c::N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-8-yl)-1,8-diaminooctane::N-(8-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}octyl)-1H,2H,3H-cyclopenta[b]quinolin-9-amine

SMILES C(CCCCNc1c2CCCc2nc2ccccc12)CCCNc1c2CCCc2nc2ccccc12

InChI Key InChIKey=KBQNIGWBLLTLRQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9046   

TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandPNGBDBM9046(N-(8-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}oct...)
Affinity DataIC50: 22nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Defense Medical Center

LigandPNGBDBM9046(N-(8-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}oct...)
Affinity DataIC50: 165nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9046(N-(8-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}oct...)
Affinity DataIC50: 22nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed