BDBM9045 Homodimeric Tacrine Analog 2b::N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-8-yl)-1,7-diaminoheptane::N-(7-{1H,2H,3H-cyclopenta[b]quinolin-9-ylamino}heptyl)-1H,2H,3H-cyclopenta[b]quinolin-9-amine

SMILES C(CCCNc1c2CCCc2nc2ccccc12)CCCNc1c2CCCc2nc2ccccc12

InChI Key InChIKey=CJYZVXNYXSEUCW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 9045   

TargetAcetylcholinesterase(Rat)
National Defense Medical Center

LigandPNGBDBM9045(N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-...)
Affinity DataIC50: 75nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Defense Medical Center

LigandPNGBDBM9045(N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-...)
Affinity DataIC50: 328nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM9045(N,N-Bis-(2,3-dihydro-1H-cyclopenta[1,2-b]quinolin-...)
Affinity DataIC50: 75nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed