BDBM9002 6-chloro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Analogue 19

SMILES CCCCCCCNc1c2CCCCc2nc2cc(Cl)ccc12

InChI Key InChIKey=XUHVEOJQELBGLL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 9002   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM9002(6-chloro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM9002(6-chloro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 13nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM9002(6-chloro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 2nMAssay Description:Inhibition of electric eel AChE preincubated for 30 mins prior to horseradish peroxidase, H2O2 and DETAPAC addition measured for 20 mins under ROS co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM9002(6-chloro-N-heptyl-1,2,3,4-tetrahydroacridin-9-amin...)
Affinity DataIC50: 16nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate preincubated for 10 mins prior to substrate addition measured every 30 seconds f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed