BDBM8992 6-fluoro-1,2,3,4-tetrahydroacridin-9-amine::Tacrine Analogue 9

SMILES Nc1c2CCCCc2nc2cc(F)ccc12

InChI Key InChIKey=FXFGIRKFQZPTMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 8992   

TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM8992(6-fluoro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50: 87nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The appearance of product was monitored at 412 nm for 5 min us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM8992(6-fluoro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50: 87nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM8992(6-fluoro-1,2,3,4-tetrahydroacridin-9-amine | Tacri...)
Affinity DataIC50: 87nMAssay Description:Inhibitory activity against human erythrocyte acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed