BDBM8951 4-Imidazol-1-ylmethyl-biphenyl-3,4-diol::4-[4-(1H-imidazol-1-ylmethyl)phenyl]benzene-1,2-diol::methyl imidazole biphenyl derivative 6

SMILES Oc1ccc(cc1O)-c1ccc(Cn2ccnc2)cc1

InChI Key InChIKey=ZBAKMRUCOWLQHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8951   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8951(4-[4-(1H-imidazol-1-ylmethyl)phenyl]benzene-1,2-di...)
Affinity DataIC50: 120nMpH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8951(4-[4-(1H-imidazol-1-ylmethyl)phenyl]benzene-1,2-di...)
Affinity DataIC50: 1.80E+3nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed