BDBM8946 3,4-Dihydro-2-(5-imidazolyl)-6,7-dimethoxy-1-methyl-naphthalene::5-[(6,7-dimethoxy-1-methyl-3,4-dihydronaphthalen-2-yl)methyl]-1H-imidazole::BW19 analog 15

SMILES COc1cc2CCC(Cc3cnc[nH]3)=C(C)c2cc1OC

InChI Key InChIKey=RSIGRRPNULEULT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8946   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8946(5-[(6,7-dimethoxy-1-methyl-3,4-dihydronaphthalen-2...)
Affinity DataIC50: 490nMpH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8946(5-[(6,7-dimethoxy-1-methyl-3,4-dihydronaphthalen-2...)
Affinity DataIC50: 6.70E+3nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed