BDBM8944 2-(1H-Imidazol-5-ylmethyl)-6,7-dimethoxy-3,4-dihydro-2H-naphthalen-1-one::2-(1H-imidazol-5-ylmethyl)-6,7-dimethoxy-1,2,3,4-tetrahydronaphthalen-1-one::GW113 analog 13

SMILES COc1cc2CCC(Cc3cnc[nH]3)C(=O)c2cc1OC

InChI Key InChIKey=NQEYJGVOWQYWHZ-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8944   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8944(2-(1H-imidazol-5-ylmethyl)-6,7-dimethoxy-1,2,3,4-t...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8944(2-(1H-imidazol-5-ylmethyl)-6,7-dimethoxy-1,2,3,4-t...)
Affinity DataIC50: 4.70E+3nMAssay Description:The 17 alpha-hydroxylase activity of CYP 17 was determined by measuring the conversion of progesterone into 17 alpha-hydroxyprogesterone and the bypr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed