BDBM8928 5-(2-Naphthyl)-1,3-oxazole::5-(naphthalen-2-yl)-1,3-oxazole::US9271963, 29::oxazole-substituted naphthalene 29

SMILES c1ncc(o1)-c1ccc2ccccc2c1

InChI Key InChIKey=UQGCSVOKHFBQIP-UHFFFAOYSA-N

Data  1 IC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8928   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8928(5-(2-Naphthyl)-1,3-oxazole | 5-(naphthalen-2-yl)-1...)
Affinity DatapH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Universitat Des Saarlandes

US Patent
LigandPNGBDBM8928(5-(2-Naphthyl)-1,3-oxazole | 5-(naphthalen-2-yl)-1...)
Affinity DataIC50: 805nMT: 2°CAssay Description:V79 MZh11B1 and V79 MZh 11B2 cells (8˙10^5 cells per well) were grown to confluency on 24-well cell culture plates with 1.9 cm^2 culture area per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent