BDBM89185 3-Amino-5-(2-diethylamino-ethyl)-5H-pyrido[4,3-b]indole-4-carbonitrile::3-amino-5-[2-(diethylamino)ethyl]-4-pyrido[4,3-b]indolecarbonitrile::3-amino-5-[2-(diethylamino)ethyl]pyrid[4,3-b]indole-4-carbonitrile::3-amino-5-[2-(diethylamino)ethyl]pyrido[4,3-b]indole-4-carbonitrile::3-azanyl-5-[2-(diethylamino)ethyl]pyrido[4,3-b]indole-4-carbonitrile::MLS000554093::SMR000146410::US10252984, Table 2.28::cid_946898

SMILES CCN(CC)CCn1c2ccccc2c2cnc(N)c(C#N)c12

InChI Key InChIKey=YEVMYZBKILWGFV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 89185   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89185(cid_946898 | 3-amino-5-[2-(diethylamino)ethyl]pyri...)
Affinity DataIC50: 9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetProbable global transcription activator SNF2L2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM89185(cid_946898 | 3-amino-5-[2-(diethylamino)ethyl]pyri...)
Affinity DataEC50:  3.38E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetG protein-coupled receptor kinase 6(Human)
Mayo Foundation

US Patent
LigandPNGBDBM89185(cid_946898 | 3-amino-5-[2-(diethylamino)ethyl]pyri...)
Affinity DataIC50: 1.88E+4nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
Go to US Patent