BDBM89034 (1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-diphenyl-sulfanylidenephosphorane;methyl sulfate::(1,2-dimethylimidazo[1,2-a]pyridin-4-ium-3-yl)-diphenyl-sulfanylidene--phosphane;methyl sulfate::(1,2-dimethylimidazo[1,2-a]pyridin-4-ium-3-yl)-diphenyl-thioxo-phosphorane;methyl sulfate::CHEMBL1598051::MLS002703110::SMR001566915::cid_56643192

SMILES Cc1c([n+]2ccccc2n1C)P(=S)(c1ccccc1)c1ccccc1

InChI Key InChIKey=DHDHZKHTNUDMEA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 89034   

TargetProthrombin(Bovine)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 6.28E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
Target26S proteasome non-ATPase regulatory subunit 14(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 5.42E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 84nMAssay Description:Displacement of [125I]Tyr10-NPS from neuropeptide S receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuropeptide S receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM89034(cid_56643192 | (1,2-dimethylimidazo[1,2-a]pyridin-...)
Affinity DataIC50: 51nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed