BDBM8886 (8E)-8-(1H-Imidazol-5-ylmethylene)-5,6,7,8-tetrahydronaphthalene-2-carbonitrile::(8E)-8-(1H-imidazol-5-ylmethylidene)-5,6,7,8-tetrahydronaphthalene-2-carbonitrile::Imidazolylmethylenetetrahydronaphthalene 3a::Imidazolylmethylenetetrahydronaphthalene 3b

SMILES N#Cc1ccc2CCCC(=Cc3cnc[nH]3)c2c1

InChI Key InChIKey=QCSHDBFRWJERMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8886   

TargetAromatase(Human)
Saarland University

LigandPNGBDBM8886((8E)-8-(1H-Imidazol-5-ylmethylene)-5,6,7,8-tetrahy...)
Affinity DataIC50: 970nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8886((8E)-8-(1H-Imidazol-5-ylmethylene)-5,6,7,8-tetrahy...)
Affinity DataIC50: 810nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8886((8E)-8-(1H-Imidazol-5-ylmethylene)-5,6,7,8-tetrahy...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8886((8E)-8-(1H-Imidazol-5-ylmethylene)-5,6,7,8-tetrahy...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed