BDBM8879 5-[(E)-(5-Fluoro-2,3-dihydro-1H-inden-1-ylidene)methyl]-1H-imidazole::5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]methyl}-1H-imidazole::Imidazolylmethyleneindane 7a::Imidazolylmethyleneindane 7b

SMILES Fc1ccc2C(CCc2c1)=Cc1cnc[nH]1

InChI Key InChIKey=PZPZHHNJIWLCNC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 8879   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 20.6nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 11.2nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 16.7nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 13.9nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 218nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataIC50: 20nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8879(5-{[(1E)-5-fluoro-2,3-dihydro-1H-inden-1-ylidene]m...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed