BDBM8878 5-[(E)-(7-Chloro-3,4-dihydronaphthalen-1(2H)-ylidene)-methyl]-1H-imidazole::5-{[(1E)-7-chloro-1,2,3,4-tetrahydronaphthalen-1-ylidene]methyl}-1H-imidazole::Imidazolylmethylenetetrahydronaphthalene 6a

SMILES Clc1ccc2CCCC(=Cc3cnc[nH]3)c2c1

InChI Key InChIKey=IXZHKLPXEBEKJV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8878   

TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

LigandPNGBDBM8878(5-{[(1E)-7-chloro-1,2,3,4-tetrahydronaphthalen-1-y...)
Affinity DataIC50: 18.7nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

LigandPNGBDBM8878(5-{[(1E)-7-chloro-1,2,3,4-tetrahydronaphthalen-1-y...)
Affinity DataIC50: 47.3nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetAromatase(Human)
Saarland University

LigandPNGBDBM8878(5-{[(1E)-7-chloro-1,2,3,4-tetrahydronaphthalen-1-y...)
Affinity DataIC50: 120nMAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Saarland University

LigandPNGBDBM8878(5-{[(1E)-7-chloro-1,2,3,4-tetrahydronaphthalen-1-y...)
Affinity DataAssay Description:The enzyme activity was assayed by monitoring the conversion of deoxycorticosterone to corticosterone in the presence of inhibitor compounds. The pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2006
Entry Details Article
PubMed