BDBM8864 3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methoxyphenyl)-1-(3-methylphenyl)urea::N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-methoxyphenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 90

SMILES COc1cc(NC(=O)Nc2cccc(C)c2)ccc1-c1csc2ncnc(N)c12

InChI Key InChIKey=AUEDINJRBZYSTK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8864   

TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM8864(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methox...)
Affinity DataIC50: 140nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8864(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methox...)
Affinity DataIC50: 100nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8864(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methox...)
Affinity DataIC50: 180nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8864(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methox...)
Affinity DataIC50: 180nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8864(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methox...)
Affinity DataIC50: 182nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8864(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-methox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed