BDBM8856 3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]pyrimidin-5-yl]phenyl}-1-(3-methylphenyl)urea::N-{4-[4-Amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]-pyrimidin-5-yl]phenyl}-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 82

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2c(Cc3cccnc3)sc3ncnc(N)c23)c1

InChI Key InChIKey=KNXNQDZKPNJJEY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8856   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8856(3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]p...)
Affinity DataIC50: 34nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8856(3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]p...)
Affinity DataIC50: 790nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8856(3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]p...)
Affinity DataIC50: 250nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8856(3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]p...)
Affinity DataIC50: 794nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8856(3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]p...)
Affinity DataIC50: 33.9nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8856(3-{4-[4-amino-6-(pyridin-3-ylmethyl)thieno[2,3-d]p...)
Affinity DataIC50: 251nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed