BDBM8843 Methyl 3-[({[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)phenyl]amino}carbonyl)amino]benzoate::Thienopyrimidine deriv. 25::methyl 3-{[(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)carbamoyl]amino}benzoate

SMILES COC(=O)c1cccc(NC(=O)Nc2ccc(cc2)-c2c(C)sc3ncnc(N)c23)c1

InChI Key InChIKey=JAUMZCPURODLNC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8843   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8843(methyl 3-{[(4-{4-amino-6-methylthieno[2,3-d]pyrimi...)
Affinity DataIC50: 290nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8843(methyl 3-{[(4-{4-amino-6-methylthieno[2,3-d]pyrimi...)
Affinity DataIC50: 43nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8843(methyl 3-{[(4-{4-amino-6-methylthieno[2,3-d]pyrimi...)
Affinity DataIC50: 510nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8843(methyl 3-{[(4-{4-amino-6-methylthieno[2,3-d]pyrimi...)
Affinity DataIC50: 42.7nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8843(methyl 3-{[(4-{4-amino-6-methylthieno[2,3-d]pyrimi...)
Affinity DataIC50: 513nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8843(methyl 3-{[(4-{4-amino-6-methylthieno[2,3-d]pyrimi...)
Affinity DataIC50: 295nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed