BDBM8812 3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-phenylurea::N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -phenylurea::Thienopyrimidine deriv. 9

SMILES Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2ccccc2)cc1

InChI Key InChIKey=LIEYHNMAMBIXPW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 8812   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8812(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 36nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8812(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8812(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8812(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8812(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 36.3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8812(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 32.4nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed