BDBM87147 CHEMBL1254823::N-[2-[1-(3-chlorophenyl)-4-keto-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-4-fluoro-benzamide;2,2,2-trifluoroacetic acid::N-[2-[1-(3-chlorophenyl)-4-oxidanylidene-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-4-fluoranyl-benzamide;2,2,2-tris(fluoranyl)ethanoic acid::N-[2-[1-(3-chlorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]ethyl]-4-fluorobenzamide;2,2,2-trifluoroacetic acid::VU0405264-1::cid_46939875

SMILES Fc1ccc(cc1)C(=O)NCCN1CCC2(CC1)N(CNC2=O)c1cccc(Cl)c1

InChI Key InChIKey=WJSLAVJCDJVONB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 87147   

TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87147(cid_46939875 | VU0405264-1 | N-[2-[1-(3-chlorophen...)
Affinity DataIC50: 70nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87147(cid_46939875 | VU0405264-1 | N-[2-[1-(3-chlorophen...)
Affinity DataIC50: 3.47E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87147(cid_46939875 | VU0405264-1 | N-[2-[1-(3-chlorophen...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87147(cid_46939875 | VU0405264-1 | N-[2-[1-(3-chlorophen...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed