BDBM87119 (1R,2R)-N-[(1S)-2-[4-(5-bromo-2-keto-3H-benzimidazol-1-yl)piperidino]-1-methyl-ethyl]-2-phenyl-cyclopropanecarboxamide;2,2,2-trifluoroacetic acid::(1R,2R)-N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-2-phenyl-cyclopropane-1-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid::(1R,2R)-N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]propan-2-yl]-2-phenyl-1-cyclopropanecarboxamide;2,2,2-trifluoroacetic acid::(1R,2R)-N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-2-phenylcyclopropane-1-carboxamide;2,2,2-trifluoroacetic acid::VU0359595 (2)::VU0359595-1::cid_53470193

SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)[C@@H]1C[C@H]1c1ccccc1

InChI Key InChIKey=JSVNNLRZCJAYTQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 87119   

TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87119((1R,2R)-N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3...)
Affinity DataIC50: 6.40E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D2(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87119((1R,2R)-N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3...)
Affinity DataIC50: 1.10E+3nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87119((1R,2R)-N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3...)
Affinity DataIC50: 15nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87119((1R,2R)-N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3...)
Affinity DataIC50: 4nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2012
Entry Details
PCBioAssay
TargetPhospholipase D1(Human)
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM87119((1R,2R)-N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3...)
Affinity DataIC50: 3.70nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetPhospholipase D(Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)
Vanderbilt University

LigandPNGBDBM87119((1R,2R)-N-[(2S)-1-[4-(5-bromanyl-2-oxidanylidene-3...)
Affinity DataIC50: 2.00E+4nMpH: 7.5Assay Description:In brief, 6 nM purified PldA was incubated with liposomes containing 90 μM 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol), 10 μM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed